The study of sex chromosome aberrations should indicate whether the presence of additional X or Y chromosomes is associated with 2D:4D levels. Further family studies will be needed to test whether the transmission mode of 2D:4D is consistent with X-linked or Y-linked inheritance. Directions for research are discussed, such as investigating possible influences of the sex chromosomes on the expression of 2D:4D. Supplemental analyses showed that, consistent with a prediction from sex-hormone transfer theory, women from opposite-sex fraternal twin pairs had significantly lower (more male-typical) 2D:4D than women from same-sex fraternal twin pairs. Existing literature and recent research show accumulating evidence on 2D:4D ratio showing correlations with various phenotypic traits in humans. The best-fitting structural equation model indicated that the contributions to individual differences in 2D:4D are 81% additively genetic, 19% nonshared environmental, and 0% shared environmental. Abstract Digit ratios, especially 2D:4D ratio, a potential proxy marker for prenatal androgen exposure shows sexual dimorphism. Both basic and advanced approaches for estimating heritability concordantly suggested that the trait is substantially heritable. The present study investigated the 2D:4D ratio of 44 men and 70 women from 36 identical and 21 fraternal twin pairs. Over the past few years, an accumulating research program has shown 2D:4D to be related to a multitude of sex-dependent, hormonally influenced psychological and behavioral traits. This somatic trait has been proposed as a biomarker for the organizational (permanent) effects of prenatal testosterone on the brain and behavior. The second-to-fourth digit ratio (2D:4D) is sexually dimorphic in humans, such that men on average have a lower 2D:4D than women. 1641 Accesses 4 Citations Metrics Abstract The study aimed to determine the relationship between digit ratios among a motherchild population in Ghana.
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